Ibuprofen linked to male infertility
- Author: Ismael Montgomery Jan 10, 2018,
Jan 10, 2018, 0:25
Ibuprofen has always been a drug of choice for chronic pain and arthritis.
"The effects were very mild even after six weeks of regular consumption of ibuprofen, which is longer than is usually recommended in practice, so this data should not concern men who occasionally take ibuprofen for pain relief", added Imperial College London senior clinical lecturer in endocrinology Ali Abbara.
When the researchers measured the testosterone/luteinizing hormone (LH) ratio in the participants, they found that the ibuprofen group experienced an 18 percent ratio decrease after 14 days.
When struggling to get pregnant, couples will immediately try to find the source of the issue, but a small new study has revealed that ibuprofen could be a potential sperm killer, and it's something all trying couples should read.
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This led, they said, to compensated hypogonadism, a condition linked to reproductive and other health problems normally found in elderly men. The painkiller users could potentially face prolonged low testosterone levels after the body loses its ability to compensate, leading to a host of health conditions including muscle weakness and loss, low fertility, and other issues. Ibuprofen, also known as an non-steroidal anti-inflammatory drug, has a negative impact on the testicles of young men, according to CNN. Each dose was 600mg, equivalent to three over-the-counter pills.
This resulted in hypogonadism, which is associated with infertility and increased risk of cardiovascular diseases like stroke and heart failure. It's an important finding to keep in mind-but also comes with some caveats, and isn't exactly a clarion call to ditch painkillers like ibuprofen (sold under brand names like Advil and Motrin) altogether. This amount was used to represent the dose taken by athletes to manage pain. The remaining 17 volunteers were given a placebo.
The safety and efficacy of active ingredients in these products has been well documented and supported by decades of scientific study and real-world use.
The detrimental effects of daily ibuprofen were almost immediate.
It's also not clear whether the same hormonal effects would be seen in men taking lower doses of ibuprofen, or whether the effects are reversible, particularly in men who take ibuprofen for long periods, study co-author Bernard Jégou, director of the National Institute for Research on Environmental and Occupational Health in France, told CNN.